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The indication of Viagra (Sildenafil citrate) is erectile dysfunction. Erectile dysfunction is the failure to attain or sustain a penile erection adequate for satisfactory sexual performance. Sexual stimulation is needed in order for Viagra to be effective.
Viagra or Sildenafil citrate is orally administered. The dosage of Viagra differs depending upon the age bracket and other existing illness.
For adults, the recommended dose is 50 mg to be taken, as needed, approximately 1 hour before sexual activity. The dose may be increased to a maximum recommended dose of 100 mg or decreased to 25 mg based on effectiveness and tolerance. 100 mg is the maximum recommended daily dose with a the maximum recommended dosing frequency of once a day. Elderly patients do not require dosage adjustments.
For patients with severe renal impairment (creatinine clearance < 30 mL/min), a 25 mg dose must be considered. Patients with mild to moderate renal impairment do not require dosage requirements.
Sildenafil clearance is reduced in patients with hepatic impairment, A 25 mg dose should be considered for these patients.
Patients receiving concomitant therapy with ritonavir are recommended not to go above a maximum single dose of 25 mg within a period of 2 days. A starting dose of 25 mg should be considered in patients receiving concomitant treatment with CYP3A4 inhibitors like erythromycin, saquinavir, ketoconazole, itraconazole.
In order to minimize the potential for developing postural hypertension, patients should be stable on alpha blocker therapy before starting sildenafil treatment. In addition, starting Viagra at lower doses must be considered.
In a clinical study of healthy volunteers with a single dosage of up to 800 mg, adverse effects were similar to those seen at lower doses but incidence rates were increased. Go see your doctor for he’ll know what is best for you.